The Space Between Part One: Call and Response by Matthew Sturges (writer), Luca Rossi (artist), and Lee Loughridge (colors) - There seems to be two throughlines developing in this volume. The first is the impact Peter, Fig's father, is having on the gang of five: Fig, Harry, Cressida, Poet, Ann. Fig and Harry are the only ones who seem to affected. She confronts her dad, then he confronts Harry, and then he completes the circle by confronting her.
The second is the story of Rina, who was first seen in v1 at her farewell party, just before she was escorted from the House. She has been taken by that mysterious couple, the Conception, to what seems to be the City in the Space Between. She meets with someone who seems to have plans for her.
The City in the Space Between by Matthew Sturges (writer), Jim Fern (artist), and Lee Loughridge (colors) - The universe this series takes place in expands. Peter, Fig's father, tells the story of the city. There's nothing particularly horrific about the tale but there is an element of the fantastic.
House of Mystery is published by Vertigo, an imprint of DC Comics